A rare recessive autosomal condition has an allele frequency of q = 0.01 in a large, randomly mating population. The inbreeding coefficient of a child of first cousins is F = 1/16. How many times greater than the risk for a child of unrelated parents is the risk of the condition for a child of first cousins?

BiologyHardHigh School (11–12)Heredity and Evolution › Evolution Olympiad

A rare recessive autosomal condition has an allele frequency of $q = 0.01$ in a large, randomly mating population. The inbreeding coefficient of a child of first cousins is $F = \tfrac{1}{16}$ . How many times greater than the risk for a child of unrelated parents is the risk of the condition for a child of first cousins?

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