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Which molecule carries the plan of a living thing, a protein or a nucleic acid? You follow three famous experiments, then build DNA and RNA from their nucleotides and use the rules of base pairing to count. At the end you see how two metres of DNA are packed into one nucleus. It serves the Indian syllabus (NCERT, NEET) and the matching topic of A-Level, IB and AP.
A cell must copy all of its DNA before it divides, and it must read a gene before it can make a protein. You see how Meselson and Stahl showed that each new DNA keeps one old strand. Then you meet the enzymes of replication, the leading and the lagging strand, and the way a gene is copied into RNA and finished in the nucleus. It serves the Indian syllabus (NCERT, NEET) and the matching topic of A-Level, IB and AP.
Four letters must write the names of twenty amino acids. You read the genetic code, see what a change of one letter does, and follow a polypeptide as the ribosome builds it. Then you switch the lac operon on and off, and meet the Human Genome Project and the DNA fingerprint. It serves the Indian syllabus (NCERT, NEET) and the matching topic of A-Level, IB and AP.
Beyond the textbook: how a labelled-nitrogen experiment is designed and what each model of replication predicts. How to reason about every mutant of the lac operon, how a change of one base changes a codon, and how to read a gel and count copies in PCR. Twelve harder problems and a full timed paper, at the level of A-Level Biology, IB Higher Level and the Olympiad.