Try it on paper first. A hint, the key idea and the worked solution are here when you need them.
In a model of the medulla, the cortex is at mOsmol/L and each level below it adds mOsmol/L. A loop of Henle reaches as many levels as its length allows.
The osmolarity of the interstitial fluid rises from mOsmol/L in the cortex to about mOsmol/L in the inner medulla. The descending limb is permeable to water. The ascending limb is impermeable to water and lets electrolytes out. The vasa recta runs beside the loop in a counter current. Only water leaves the collecting duct, so the amount of solute stays the same: is constant.
Have you tried it?
Work it out on paper first. It is fine to get stuck or make a mistake: that is how we learn. When you are ready, go through the solution one step at a time, and check each step against your own.
Given. Cortex: mOsmol/L. Step: mOsmol/L for each level.
Plan. Use for levels.
Step 1. Two levels. mOsmol/L.
Step 2. Four levels. mOsmol/L.
Step 3. Six levels. mOsmol/L.
Step 4. Times the cortex. times.
Answer: ; ; mOsmol/L; times.
Check. The long loop gives the NCERT value of mOsmol/L and a urine nearly four times as concentrated as the filtrate.
Watch out. The step of is a number of the model. Real kidneys do not have equal steps.
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