Try it on paper first. A hint, the key idea and the worked solution are here when you need them.
L of fluid at mOsmol/L enters the collecting ducts. The ducts take out only water.
The osmolarity of the interstitial fluid rises from mOsmol/L in the cortex to about mOsmol/L in the inner medulla. The descending limb is permeable to water. The ascending limb is impermeable to water and lets electrolytes out. The vasa recta runs beside the loop in a counter current. Only water leaves the collecting duct, so the amount of solute stays the same: is constant.
Have you tried it?
Work it out on paper first. It is fine to get stuck or make a mistake: that is how we learn. When you are ready, go through the solution one step at a time, and check each step against your own.
Given. Volume in: L at mOsmol/L.
Plan. The solute stays: .
Step 1. At . L.
Step 2. Water out. L.
Step 3. At . L.
Answer: L; L; L.
Check. A urine four times as concentrated has a quarter of the volume: L.
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