Mutations and Genetic Disorders

Name: Mutations and Genetic Disorders
Author: StemPy Lab

A change of one letter in a gene can change a protein, and a change in a whole chromosome can change a life. You learn what a mutation is and what kinds there are. Then you meet the disorders that follow a Mendelian pattern, such as thalassaemia, and the disorders caused by a wrong number of chromosomes, such as Down syndrome. You also learn the chi-square idea, which tells you whether a ratio fits. It serves the Indian syllabus (NCERT, NEET) and the matching topic of A-Level, IB and AP.

3 lessons, about 1 h 30 min3 simulations12 problems3 practice questionsPython in every lesson

Created by StemPy Lab

Course outline (3 lessons)

Lesson 1about 30 min
Mutation: from a changed base to a changed protein
A mutation is a sudden change in the DNA of a cell. This lesson sorts mutations by size: a single base, a few bases, a piece of a chromosome and a whole chromosome. You find out which changes alter a protein and which do not.
1 simulation1 practice question2 Python programs4 problems1 Python lab
Read the lesson
Lesson 2about 30 min
Mendelian disorders in humans
Some disorders follow the laws of Mendel because one gene is changed. This lesson covers the common Mendelian disorders of humans, thalassaemia in detail, and shows how to work out the risk for a family with a Punnett square and a pedigree.
1 simulation1 practice question1 Python program5 problems
Read the lesson
Lesson 3about 30 min
Chromosomal disorders and the chi-square idea
A wrong number of chromosomes can change a life. This lesson explains non-disjunction and the three syndromes of the syllabus: Down, Turner and Klinefelter. It ends with the chi-square idea, which tells you whether a ratio from a real cross really fits.
1 simulation1 practice question2 Python programs3 problems1 Python lab1 question set1 note
Read the lesson

Test Your Learning

Mutations and Genetic Disorders: Chapter Test

20 questions · 15 min

Not started

Your teacher

StemPy Lab

← Principles of Inheritance and Variation

← Chromosomes, Linkage and SexNext →

More onHeredity and Evolution › Principles of Inheritance and Variation

Discussion (0)

Loading…

Mutations and Genetic Disorders

Course outline (3 lessons)

Mutation: from a changed base to a changed protein

Mendelian disorders in humans

Chromosomal disorders and the chi-square idea

Test Your Learning

Your teacher

1 follower

Discussion (0)

Want to go further?