The hormones made outside the main glands, by the heart, the kidney and the gut. How a hormone finds its cell, and why a peptide hormone and a steroid hormone act in different ways. Then how feedback loops and the two control systems work together to keep the body steady.
3 lessons, about 1 h 25 min3 simulations10 problems3 practice questionsPython in every lesson
The wall of the heart makes ANF, which lowers the blood pressure. The kidney makes erythropoietin, which raises the number of red cells. The stomach and the small intestine make gastrin, secretin, CCK and GIP, which control the digestive juices. Many tissues also make growth factors.
A hormone acts only on cells that carry its receptor. Peptide hormones and the amine adrenaline bind to receptors in the cell membrane and work through second messengers such as cyclic AMP. Steroid hormones and the thyroid hormones pass into the cell, bind to receptors inside, and change the genes.
The nervous system and the endocrine system together coordinate the body. The hypothalamus joins them. Negative feedback keeps a level steady around a set point, and positive feedback drives a process to its end, as in childbirth. Hormones often work in opposite pairs, such as insulin and glucagon.
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