Match the disorders in List-I with their causes in List-II. List-I (Disorder) A. Sickle-cell anaemia B. Phenylketonuria C. Haemophilia D. Thalassemia List-II (Cause) I. The enzyme that converts phenylalanine into tyrosine is missing II. Too few globin molecules are made III. Glutamic acid is replaced by valine at the sixth position of the $\beta$-globin chain IV. A protein of the cascade of proteins for blood clotting is affected