Try it on paper first. A hint, the key idea and the worked solution are here when you need them.
These stages of the life cycle of Plasmodium are in the wrong order.
Malaria is caused by Plasmodium. Sporozoites enter the human at the bite, multiply in the liver and then in the red blood cells, which burst and release haemozoin. Gametocytes form in the red cells and are sucked up by the female Anopheles, where the gametes fuse in the gut. Tertian fever returns every 2 days and quartan fever every 3 days.
Have you tried it?
Work it out on paper first. It is fine to get stuck or make a mistake: that is how we learn. When you are ready, go through the solution one step at a time, and check each step against your own.
Step 1. (a) The order is: (ii) sporozoites enter the blood; (iii) the parasite multiplies in the liver cells; (i) the red blood cells burst and release haemozoin; (v) gametocytes form in the red blood cells; (iv) the gametes fuse in the gut of the mosquito; (vi) the sporozoites move to the salivary glands.
Step 2. (b) Stages (iv) and (vi) happen in the mosquito.
Step 3. (c) The sporozoites from the salivary glands.
Answer: (ii), (iii), (i), (v), (iv), (vi); the stages (iv) and (vi) are in the mosquito; the sporozoites pass to the next human.
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