Try it on paper first. A hint, the key idea and the worked solution are here when you need them.
Patient A has P. vivax malaria. The first fever comes on day , and the fever returns every hours. Patient B has P. malariae malaria. The first fever comes on day , and the fever returns every hours. Count the fevers in the first days, counting day .
Malaria is caused by Plasmodium. Sporozoites enter the human at the bite, multiply in the liver and then in the red blood cells, which burst and release haemozoin. Gametocytes form in the red cells and are sucked up by the female Anopheles, where the gametes fuse in the gut. Tertian fever returns every 2 days and quartan fever every 3 days.
Have you tried it?
Work it out on paper first. It is fine to get stuck or make a mistake: that is how we learn. When you are ready, go through the solution one step at a time, and check each step against your own.
Given. A: first fever on day , gap days. B: first fever on day , gap days. Period: days to .
Plan. List the days of fever and count them.
Step 1. Patient A. The days are . That is fevers. Day is outside the period.
Step 2. Patient B. The days are . That is fevers.
Step 3. The difference. .
Answer: fevers; fevers; more.
Check. The formula gives and .
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