Try it on paper first. A hint, the key idea and the worked solution are here when you need them.
In this problem, a person with a normal thyroid has a basal metabolic rate of 1500 kcal in a day. Assume that the rate falls in hypothyroidism by , or .
The thyroid makes T4 and T3, which need iodine. TSH controls the thyroid, and the thyroid hormones act back on the hypothalamus and pituitary by negative feedback. Too little iodine gives a goitre with a high TSH. Too much thyroid hormone, as in Graves' disease, gives a high metabolic rate.
Have you tried it?
Work it out on paper first. It is fine to get stuck or make a mistake: that is how we learn. When you are ready, go through the solution one step at a time, and check each step against your own.
Given. Normal rate: kcal in a day. The falls are assumed values.
Plan. Keep the share that is left.
Step 1. . Left: . kcal.
Step 2. . Left: . kcal.
Step 3. . Left: . kcal.
Answer: kcal; kcal; kcal in a day.
Check. A larger fall leaves a smaller rate.
Watch out. The numbers are chosen to show the method. The thyroid hormones regulate the rate of energy use, and the real fall differs from person to person.
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