A student writes six pairs. Decide which are right, and correct the wrong ones…
Contributed by StemPy LabTry it on paper first. A hint, the key idea and the worked solution are here when you need them.
A student writes six pairs. Decide which are right, and correct the wrong ones.
(1) Bt cotton: the genes cryIAc and cryIIAb, for the corn borer.
(2) Insulin: two chains joined by disulphide bridges, and no C peptide when mature.
(3) Hepatitis B vaccine: made in E. coli.
(4) Gene therapy for ADA deficiency: a retroviral vector, the first case in 1990.
(5) Alpha-1-antitrypsin: treats emphysema.
(6) Animals for toxicity tests: made less sensitive to toxic substances.
Need a reminder? The key ideaShow
The chapter pairs an application with an organism, a product and a tool. Bt cotton: Bacillus thuringiensis, genes cryIAc and cryIIAb, cotton bollworms. Corn borer: cryIAb. Insulin: chains A and B, the C peptide removed, E. coli, 1983. Hepatitis B vaccine: yeast. ADA gene therapy: lymphocytes, retroviral vector, 1990. Alpha-1-antitrypsin: emphysema. Rosie: 1997, human alpha-lactalbumin. Basmati, neem and turmeric: biopiracy and patents.
The worked solution
Have you tried it?
Work it out on paper first. It is fine to get stuck or make a mistake: that is how we learn. When you are ready, go through the solution one step at a time, and check each step against your own.
Step 1. (1) Wrong. The genes cryIAc and cryIIAb are for the cotton bollworms. The corn borer needs cryIAb.
Step 2. (2) Right.
Step 3. (3) Wrong. The hepatitis B vaccine is produced from yeast.
Step 4. (4) Right.
Step 5. (5) Right.
Step 6. (6) Wrong. The animals are made more sensitive, so the test takes less time.
Answer: pairs 2, 4 and 5 are right. Pairs 1, 3 and 6 are corrected as above.
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