Try it on paper first. A hint, the key idea and the worked solution are here when you need them.
A DNA polymerase adds nucleotides only to a 3′ end, so a new strand grows 5′ to 3′. The leading strand is made in one piece. The lagging strand is made as Okazaki fragments, which DNA ligase joins. An origin starts two forks, and the copying takes .
Have you tried it?
Work it out on paper first. It is fine to get stuck or make a mistake: that is how we learn. When you are ready, go through the solution one step at a time, and check each step against your own.
Given. (a) base pairs, origin, forks at base pairs a second. (b) base pairs, forks at base pairs a second, hours.
Plan. Time is the base pairs divided by the total speed of all the forks.
Step 1. (a) Total speed: base pairs a second. Time: s, which is min.
Step 2. (b) In hours, which is s, each fork copies base pairs. An origin has two forks, so it copies base pairs.
Step 3. Origins: . We cannot use part of an origin, so we round up to 21.
Answer: min; origins.
Check. NCERT says that is copied in about 18 minutes, which is close to min.
Watch out. Rounding down to 20 origins would not finish in time.
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